Study on the Aggregation of Fluorinated Surfactant FC-134 on the Surface of DNA

The aggregation of perfluoroalkylsulfonyl quaternary ammonium iodide (FC134) on DNA was studied by spectral method. The results showed that it is a good way to determine DNA with FC134 by RLS method. This method is reliable, precise and simple. FT-IR spectra and UV-spectra were used to study the mechanisms of the interaction. The results indicated that the conformation of the DNA has changed during the interaction because the microenvironment of DNA changed.