کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1904395 1534485 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Duplicate use of angiotesin-converting enzyme (ACE) inhibitors in a community-dwelling elderly population in Poland
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Duplicate use of angiotesin-converting enzyme (ACE) inhibitors in a community-dwelling elderly population in Poland
چکیده انگلیسی

In this paper the data on the duplicate use of ACE inhibitors among a community-dwelling elderly population are presented. Using a questionnaire, 1000 subjects were interviewed concerning the use of drugs, 654 females, mean ± SD age: 72.6 ± 6.5 years. They were divided into two groups: Group A (5%) taking at least two ACE inhibitors (n = 50) and Group B: those who used either a single ACE inhibitor or no ACE inhibitor (n = 950). In Group A, 49 individuals were taking two different ACE inhibitors concomitantly and one was using three. The most commonly used ACE inhibitor was enalapril (29 of 50 subjects). Subjects in Group A consumed significantly more drugs, both of prescription (Rx) and nonprescription (OTC), compared to those in Group B (total means: 8.4 ± 2.8 vs. 6.7 ± 3.2; p < 0.01, Rx means: 6.3 ± 2.5 vs. 5.2 ± 2.8, p < 0.05, OTC means: 2.0 ± 1.6 vs. 1.6 ± 1.5, p < 0.05). Also, they were more likely to have consulted a cardiologist (17/50 vs. 201/950, p < 0.05). The duplicate use of ACE inhibitors in 5% of a population of community-dwelling elderly patients seems to be caused by both poor doctor-doctor communication and polypharmacy. This phenomenon could possibly be dangerous especially when potential additive adverse effects are taken into account.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Gerontology and Geriatrics - Volume 44, Supplement, 2007, Pages 295-301