کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1915080 | 1645460 | 2009 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Grey matter pathology in clinically early multiple sclerosis: Evidence from magnetic resonance imaging
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Grey matter pathology in clinically early multiple sclerosis: Evidence from magnetic resonance imaging Grey matter pathology in clinically early multiple sclerosis: Evidence from magnetic resonance imaging](/preview/png/1915080.png)
چکیده انگلیسی
In multiple sclerosis (MS) it is emerging that the most visible element of pathology, white matter (WM) lesions, represents only a fraction of the disease burden borne by the brain; non-lesional WM is also damaged, as is the grey matter (GM). Evidence is also accruing that GM damage may be a major determinant of longer-term outcomes in MS, and that such damage occurs from the earliest clinical stages of the disease. In this review, we focus on the early stages of relapse onset MS, considering the nature, extent and evolution of GM pathology, as determined using magnetic resonance imaging.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Neurological Sciences - Volume 282, Issues 1–2, 15 July 2009, Pages 5–11
Journal: Journal of the Neurological Sciences - Volume 282, Issues 1–2, 15 July 2009, Pages 5–11
نویسندگان
Declan Chard, David Miller,