کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1916374 | 1535210 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Treatment of Susac syndrome with gamma globulin and corticosteroids
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Treatment of Susac syndrome with gamma globulin and corticosteroids Treatment of Susac syndrome with gamma globulin and corticosteroids](/preview/png/1916374.png)
چکیده انگلیسی
Susac syndrome is a rare vasculopathy characterized by visual, hearing, and cognitive dysfunction. Optimal treatment is unknown, but many patients require chemotherapy to control disease activity. We describe two patients with Susac syndrome and their response to intravenous immune globulin (IVIg) and corticosteroids. Both patients improved following acute treatment with IVIg and intravenous methylprednisolone (IVMP), and no further relapses were observed. One patient showed significant improvement in hearing and MRI lesions shortly following acute treatment. Treatment with IVIg and corticosteroids provides a therapeutic option that avoids the toxicities of chemotherapy and suggests the possible importance of pathologic antibodies in the pathogenesis of Susac syndrome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Neurological Sciences - Volume 251, Issues 1â2, 21 December 2006, Pages 17-22
Journal: Journal of the Neurological Sciences - Volume 251, Issues 1â2, 21 December 2006, Pages 17-22
نویسندگان
Robert J. Fox, Fiona Costello, Alexander R. Judkins, Steven L. Galetta, Albert M. Maguire, Brian Leonard, Clyde E. Markowitz,