کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1916580 1535213 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Conjugate eye movements and gamma power modulation of the EEG in persistent vegetative state
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Conjugate eye movements and gamma power modulation of the EEG in persistent vegetative state
چکیده انگلیسی

BackgroundPower in the gamma band EEG increases during saccades in normal subjects.ObjectiveTo develop a potential method to quantify signs of cortical responsiveness in persistent vegetative state (PVS) we quantified gamma range EEG in association with conjugate slow ballistic eye movements (SBEM).MethodsThe EEG and the simultaneous electro-oculogram were recorded in 14 (8F/6M) PVS patients. Clinical scoring was based on the Glasgow Coma Scale (GCS) and Coma Rating Scale (CRS). The Wavelet Transform, followed by Hilbert transform was applied to the EEG and gamma power distribution was quantified relative to the timing of an eye movement. We correlated the clinical and the neurophysiological measures.ResultsGamma activity was present in all PVS patients. Its power was modulated in association with eye movements only in less severely affected patients, with minimum power prior to, and maximum power during the eye movement. In severely affected patients there was no evidence of a temporal relationship between gamma power and the phase of the eye movement.ConclusionsDetecting changes in the time course of gamma power in relation to conjugate ballistic eye movements provides a quantitative neurophysiological method for prospective longitudinal studies to explore if the preservation of this CNS function relates to the potential for recovery in PVS patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Neurological Sciences - Volume 246, Issues 1–2, 15 July 2006, Pages 65–69
نویسندگان
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