کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1920437 1048695 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Freezing of gait and affective theory of mind in Parkinson disease
ترجمه فارسی عنوان
یخ زدن راه رفتن و تئوری ذهنی ذهن در بیماری پارکینسون
کلمات کلیدی
بیماری پارکینسون، یخ زدن راه رفتن، نظریه ذهن، اختلال عاطفی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
چکیده انگلیسی


• Affective Theory of Mind is the ability to represent own and others' emotions.
• Freezing of gait has been associated with affective dysfunction in PD.
• The affective aspects of ToM are associated to FOG in PD.

BackgroundAffective “Theory of Mind” (ToM) is the specific ability to represent own and others' emotional states and feelings. Several studies examined affective ToM ability in patients with Parkinson's disease (PD), using the “Reading the Mind in the Eyes test” (RMET). However, there has been no agreement as to whether or not affective ToM ability is impaired in PD and such discrepancy may be due to the heterogeneous clinical presentation of PD. Affective disturbance has been linked to the akinetic-rigid form of PD and to gait disturbances, like freezing of gait (FOG). Particularly, FOG has been associated with dysfunction in striatum ability of processing affective inputs. Here we hypothesized that the presence of FOG can be associated with impaired affective ToM ability in PD patients.MethodsWe evaluated ToM by means of RMET and executive functions using the Tower Of London (ToL) test in 29 PD patients (15 with FOG and 14 without FOG) and 19 healthy age-matched subjects.ResultsOur results showed that affective ToM is abnormal in PD patients, compared to healthy subjects and that it is more impaired in patients with FOG than in patients without FOG. Further, PD patients with FOG performed worse than PD patients without FOG on the ToL test.ConclusionThe affective aspects of ToM can be associated to FOG in patients with PD, thus supporting the idea that FOG is caused by a complex interplay between motor, cognitive and affective factors, rather than being a pure motor problem.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Parkinsonism & Related Disorders - Volume 21, Issue 5, May 2015, Pages 509–513
نویسندگان
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