کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1921508 | 1048774 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Vascular pathology in patients with idiopathic Parkinson's disease
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Vascular pathology in patients with idiopathic Parkinson's disease Vascular pathology in patients with idiopathic Parkinson's disease](/preview/png/1921508.png)
چکیده انگلیسی
To study the impact of brain vessel pathology on the clinical status of Parkinson's disease (PD), in 57 consecutive patients the clinical and neuropsychological data were compared with clinical MRI signs of vascular impairment and with the ultrasound brain vessel investigations. There was a significant correlation between clinical and cognitive status and intimomedial thickness, which is an indicator of large vessel impairment. Cognitive status was significantly related to the pulsatility index (an indicator of small vessel impairment). This study provides evidence that subclinical vascular pathology could influence the clinical status by contributing to motor and cognitive dysfunction in PD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Parkinsonism & Related Disorders - Volume 15, Issue 1, January 2009, Pages 24–29
Journal: Parkinsonism & Related Disorders - Volume 15, Issue 1, January 2009, Pages 24–29
نویسندگان
Ivan Rektor, David Goldemund, Kateřina Sheardová, Irena Rektorová, Zuzana Michálková, Michal Dufek,