کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1922048 1048792 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impulse control disorders in Parkinson's disease: prevalence and possible risk factors
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Impulse control disorders in Parkinson's disease: prevalence and possible risk factors
چکیده انگلیسی

SummaryThere is an increasing awareness that impulse control disorders (ICDs), including compulsive gambling, buying, sexual behavior and eating, can occur as a complication of Parkinson's disease (PD). In addition, other impulsive or compulsive disorders including dopamine dysregulation syndrome (DDS) and punding are reported. Case reporting and prospective studies documented an association between ICDs and the use of dopamine agonists (DAs), and to a lesser extent levodopa use, while DDS occurs with higher dosages of levodopa or short-acting DAs. Data suggest that risk factors for an ICD may include male sex, younger age or younger age at PD onset, a pre-PD history of ICD symptoms, personal or family history of substance abuse or bipolar disorder, and a personality style characterized by impulsiveness. It is important that PD patients be aware that DA use may lead to the development of one or more ICDs, and clinicians monitor patients as part of routine clinical care.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Parkinsonism & Related Disorders - Volume 15, Supplement 3, December 2009, Pages S110–S113
نویسندگان
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