کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1922083 1048794 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genetics of restless legs syndrome
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Genetics of restless legs syndrome
چکیده انگلیسی
Restless legs syndrome (RLS) is a common disorder, although under-diagnosed, with a prevalence of up to 15% depending on the population sampled. Familial aggregation has been widely shown since Ekbom formerly described the condition in 1960; twin studies support a genetic contribution in the development of this disorder. Molecular genetic approaches have identified three genomic regions in RLS susceptibility, however no specific mutations have yet been identified. Herein, we review the current status of genetics in RLS, providing some methodological guidelines to help future research.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Parkinsonism & Related Disorders - Volume 12, Issue 1, January 2006, Pages 1-7
نویسندگان
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