کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1924185 1048943 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neurotransmitter localization in the neuroepithelial cells and unipolar neurons of the respiratory tract in the bichir, Polypterus bichir bichir G. ST-HIL
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Neurotransmitter localization in the neuroepithelial cells and unipolar neurons of the respiratory tract in the bichir, Polypterus bichir bichir G. ST-HIL
چکیده انگلیسی

Immunohistochemical localisation of neurotransmitters was used to determine the distribution of unipolar neurons and neuroepithelial cells (NECs) in the respiratory tract of the bichir, Polypterus bichir bichir. NECs were commonly encountered in the mucociliated epithelium of the lung. Unipolar neurons were located in the submucosal and muscle layers of the glottis. The results suggest the presence of tyrosine hydroxylase (TH) and nNOS immunoreactivities in NECs. In addition, ACh-E/nNOS and TH/nNOS nerve fibers were also found associated with these cells. Unipolar neuronal cells showed a chemical code including the presence of 5-HT, ACh-E, peptides and P2×2 receptors. The present findings indicate that nitric oxide (NO) is a primitive transmitter of neuroepithelial oxygen-sensitive chemoreceptor cells together with acetylcholine. The coexistence of ACh-E with other substances in the unipolar neurons, but not with NO, may be a property of vagal postganglionic neurons since the emergence of the cranial autonomic pathways in the earliest vertebrates. It would be interesting to know about the provenance of the nerves in contact with NECs, which appear to have a complex innervation pattern.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Histochemica - Volume 110, Issue 2, 20 March 2008, Pages 143–150
نویسندگان
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