کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1972100 1539001 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Blood oxygen affinity increases during digestion in the South American rattlesnake, Crotalus durissus terrificus
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Blood oxygen affinity increases during digestion in the South American rattlesnake, Crotalus durissus terrificus
چکیده انگلیسی

Digesting snakes experience massive increases in metabolism that can last for many days and are accompanied by adjustments in the oxygen transport cascade. Accordingly, we examined the oxygen-binding properties of the blood in the South American rattlesnake (Crotalus durissus terrificus) during fasting and 24 and 48 h after the snakes have ingested a rodent meal corresponding to 15% (± 2%) of its own body mass. In general, oxygen–hemoglobin (Hb–O2) affinity was significantly increased 24 h post-feeding, and then returned toward fasting values within 48 h post-feeding. Content of organic phosphates ([NTP] and [NTP]/[Hb]), hemoglobin cooperativity (Hill's n), and Bohr Effect (ΔlogP50/ΔpH) were not affected by feeding. The postprandial increase in Hb–O2 affinity in the South American rattlesnake can be almost entirely ascribed by the moderate alkaline tide that follows meal ingestion. In general, digesting snakes were able to regulate blood metabolites at quite constant levels (e.g., plasma osmolality, lactate, glucose, and total protein levels). The level of circulating lipids, however, was considerably increased, which may be related to their mobilization, since lipids are known to be incorporated by the enterocytes after snakes have fed. In conclusion, our results indicate that the exceptional metabolic increment exhibited by C. d. terrificus during meal digestion is entirely supported by the aerobic pathways and that among the attending cardiorespiratory adjustments, pulmonary Hb–O2 loading is likely improved due to the increment in blood O2 affinity.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology - Volume 186, August 2015, Pages 75–82
نویسندگان
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