کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1973023 1060305 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Peripheral or central administration of nitric oxide synthase inhibitor affects feeding behavior in chicks
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Peripheral or central administration of nitric oxide synthase inhibitor affects feeding behavior in chicks
چکیده انگلیسی

We investigated the effect of peripheral or central administration of NG-nitro-L-arginine methyl ester (L-NAME), a nitric oxide (NO) synthase inhibitor, on food intake in layer and broiler chicks (Gallus gallus). The intraperitoneal administration of L-NAME significantly decreased food intake in both broiler and layer chicks while the administration of D-NAME, an inactive form of L-NAME, had no effect. The intracerebroventricular (ICV) injection of L-NAME did not affect food intake in broiler chicks. However, ICV injection of L-NAME increased food intake in layer chicks while the injection of D-NAME had no effect. In addition to this, L-NAME-induced feeding was negated with the co-injection of L-arginine, suggesting that NO acts as a feeding-inhibitor signal in the brain of layer chicks. The present study revealed that administration of NO synthase inhibitor affected food intake in chicks, but the effect might be changed by chick strain and position of the injection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology - Volume 148, Issue 2, October 2007, Pages 458–462
نویسندگان
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