Effects of glycine-extended and serine13-phosphorylated forms of peptide YY on food intake in rats

► PYY(3-36)-NH2 is significantly more potent than PYY(1-36)-NH2 in reducing food intake. ► Gly-extended forms of PYY are significantly less potent than non-extended forms. ► Ser13-phosphorylation decreases the anorexigenic potency of PYY(3-36)-NH2. ► Ser13-phosphorylation does not affect the anorexigenic potency of PYY(1-36)-NH2.