کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2034084 1071990 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Aerosolized MMR vaccine: Evaluating potential transmission of components to vaccine administrators and contacts of vaccinees
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوشیمی، ژنتیک و زیست شناسی مولکولی (عمومی)
پیش نمایش صفحه اول مقاله
Aerosolized MMR vaccine: Evaluating potential transmission of components to vaccine administrators and contacts of vaccinees
چکیده انگلیسی

Although numerous operative and immunological advantages accompany aerosol immunization, potential vaccine virus transmission from the aerosol device to vaccine administrators or from aerosol vaccinees to their contacts requires further study. We conducted a clinical and serological follow-up study of vaccine administrators and matched classroom or household contacts of young adults who received the MMR vaccines by aerosol or injection. Differences in incidence of clinical adverse events between vaccinees and contacts were not statistically significant. No seroresponses to any components of MMR vaccine were noted among 25 matched contacts of persons receiving injected vaccines, and only one equivocal seroresponse was noted among 25 matched contacts of aerosol recipients. No seroresponses were observed in 3 persons who administered aerosol vaccine. The composite findings of this study provide additional evidence of the safety of this approach.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biologicals - Volume 40, Issue 4, July 2012, Pages 278–281
نویسندگان
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