Nanometric resolution magnetic resonance imaging methods for mapping functional activity in neuronal networks

• NV in diamond acts as an atomic size optically detectable spin probe.
• The probe combines high magnetic field sensitivity and nanometric resolution.
• Non-invasive mapping of functional activity in neuronal networks is one application.
• Synapse scale resolution ∼10 nm but circuit scale FoV >1 mm is possible.

This contribution highlights and compares some recent achievements in the use of k-space and real space imaging (scanning probe and wide-filed microscope techniques), when applied to a luminescent color center in diamond, known as nitrogen vacancy (NV) center. These techniques combined with the optically detected magnetic resonance of NV, provide a unique platform to achieve nanometric magnetic resonance imaging (MRI) resolution of nearby nuclear spins (known as nanoMRI), and nanometric NV real space localization.
• Atomic size optically detectable spin probe.
• High magnetic field sensitivity and nanometric resolution.
• Non-invasive mapping of functional activity in neuronal networks.