کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2094414 1082016 2008 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Signaling networks in hepatic oval cell activation
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Signaling networks in hepatic oval cell activation
چکیده انگلیسی

Oval cells are hypothesized to be the progeny of intrahepatic stem cells, also referred to as adult liver stem cells. The mechanisms by which these cells are activated to proliferate and differentiate during liver regeneration is important for the development of new therapies to treat liver disease. Oval cell activation is the first step in progenitor-dependent liver regeneration in response to certain types of injury. This review describes what is currently known about the factors involved in oval cell activation, proliferation, migration, and differentiation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Stem Cell Research - Volume 1, Issue 2, June 2008, Pages 90–102
نویسندگان
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