miR-155 regulative network in FLT3 mutated acute myeloid leukemia

• Generation of miR-155 network on FLT3-ITD+ AML utilizing data from multiple sources.
• Connections among miR-155 and master myeloid transcription factor in FLT3-ITD+ AML.
• Inhibition of FLT3-ITD decreases p-JUN and miR-155 and increases miR-155 targets.
• Inverse correlation between miR-155 and TFs (PU.1 and CEBP-beta) in FLT3-ITD+ AML.
• In vitro functional ex