کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2138681 | 1087883 | 2009 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The significance of bone marrow cell morphology and its correlation with cytogenetic features in the diagnosis of MDS-RA patients
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
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چکیده انگلیسی
Besides cytopenia, dysplasia is crucial characteristic of MDS-RA. To summarize the morphological features that contribute to the diagnosis of MDS-RA, 48 RA patients with abnormal karyotype were analyzed for the features of morphological and cytogenetical abnormalities and the relationships between them. 46 MDS-RA patients with normal karyotype and 207 patients with non-MDS anemia were enrolled into control groups. More conspicuous and diverse dysplasia can be found in abnormal karyotype MDS-RA than those in control groups (P < 0.05). Apparent dysplasia in granulocyte and megakaryocytoid lineages may provide valuable evidence for the diagnosis. Dysplasia occurred more frequently in patients with severe chromosome abnormalities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Leukemia Research - Volume 33, Issue 8, August 2009, Pages 1029–1038
Journal: Leukemia Research - Volume 33, Issue 8, August 2009, Pages 1029–1038
نویسندگان
Dandan Liu, Zixing Chen, Yongquan Xue, Dingwei Lu, Youning Zhou, Jingxia Gong, Weilin Wu, Jianying Liang, Qinfen Ma, Jinlan Pan, Yafang Wu, Yong Wang, Jun Zhang, Juan Shen,