کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2146742 | 1548370 | 2010 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks](/preview/png/2146742.png)
چکیده انگلیسی
PurposeThe majority of cancer patients will receive radiotherapy (RT), therefore, investigations into advances of this modality are important. Conventional RT dose intensities are limited by adverse responses in normal tissues and a primary goal is to ameliorate adverse normal tissue effects. The aim of these experiments is to further our understanding regarding the mechanism of radioprotection by the DNA minor groove binder, methylproamine, in a cellular context at the DNA level.Materials and methodsWe used immunocytochemical methods to measure the accumulation
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 692, Issues 1–2, 13 October 2010, Pages 49–52
Journal: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Volume 692, Issues 1–2, 13 October 2010, Pages 49–52
نویسندگان
Carl N. Sprung, Raja S. Vasireddy, Tom C. Karagiannis, Shanon J. Loveridge, Roger F. Martin, Michael J. McKay,