Photo catalogue for the classification of cell colonies in the Syrian hamster embryo (SHE) cell transformation assay at pH 7.0

This catalogue is a display of Syrian hamster embryo (SHE) cell colony photos representative of the cell transformation assay (CTA) carried out at pH 7.0.It is intended as a visual aid for the identification and the scoring of cell colonies in the conduct of the assay.A proper training from experienced personnel together with the protocol reported in this issue and the present photo catalogue will support method transfer and consistency in the assay results.

► A photo catalogue was produced during the ECVAM prevalidation study on cell transformation assay.
► The aim of this photo catalogue is to standardize the scoring of colonies at pH 7.0.
► It includes examples of normal colonies, transformed colonies and colonies with mixed morphology.