کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2149031 1089595 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Establishment of the comet assay in the freshwater snail Biomphalaria glabrata (Say, 1818)
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
پیش نمایش صفحه اول مقاله
Establishment of the comet assay in the freshwater snail Biomphalaria glabrata (Say, 1818)
چکیده انگلیسی

The single cell gel eletrophoresis or the comet assay was established in the freshwater snail Biomphalaria glabrata. For detecting DNA damage in circulating hemocytes, adult snails were irradiated with single doses of 2.5, 5, 10 and 20 Gy of 60Co gamma radiation. Genotoxic effect of ionizing radiation was detected at all doses as a dose-related increase in DNA migration. Comet assay in B. glabrata demonstrated to be a simple, fast and reliable tool in the evaluation of genotoxic effects of environmental mutagens.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mutation Research/Genetic Toxicology and Environmental Mutagenesis - Volume 654, Issue 1, 30 June 2008, Pages 58–63
نویسندگان
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