کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2152664 1090130 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
5% lidocaine medicated plasters vs. sympathetic nerve blocks as a part of multimodal treatment strategy for the management of postherpetic neuralgia: A retrospective, consecutive, case-series study
ترجمه فارسی عنوان
5٪ پلاستر درمان دارویی لیدوکائین در مقابل بلوک های عصبی سمپاتیک به عنوان بخشی از استراتژی درمان چندجمله ای برای مدیریت نورالژی پس از آن: یک مطالعه گذشته نگر، دنباله دار، سری مورد
کلمات کلیدی
نورالژی پسا گرا مقیاس رتبه بندی عددی، بلوک عصبی سمپاتیک، گاباپنتین، داروهای ضدافسردگی سه حلقه ای
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی

Introduction5% lidocaine medicated plasters (5% LMP) have been appointed as a first-line treatment for post-herpetic neuralgia (PHN), while formerly used sympathetic nerve blocks (SNBs) were recently denied their clinical efficacy. The aim of this study was to compare the results of PHN management with the use of SNBs and 5% LMP as a first-line treatment.Material and methodsThis study was designed as a retrospective, consecutive, case-series study. Data of 60 consecutive PHN patients with allodynia treated with the use of SNBs and 60 subsequent patients managed with 5% LMP were analyzed. Pain severity after 8 weeks was assessed to recognize the results of the implemented therapy, with numeric rating scale (NRS) score <3 or =3 considered a success. Additionally, the number of pain-free patients (NRS = 0) after 8 weeks were identified in both groups and compared.ResultsThe rate of failures in SNBs and 5% LMP group was similar (18.9% vs. 27.1% of poor treatment results, respectively), with the average change in NRS of 5.88 ± 2.41 in nerve blocks and 5.01 ± 1.67 in lidocaine group (p = 0.02). Significant difference was also noted in the rates of pain-free patients: 20 patients (34.4%) treated with SNBs and 8 (13.5%) using 5% LMP were pain-free after 8 weeks of treatment.ConclusionIt may be concluded that SNBs may still be considered useful in PHN management, as it appears that in some cases this mode of treatment may offer some advantages over 5% LMP.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurologia i Neurochirurgia Polska - Volume 49, Issue 1, January–February 2015, Pages 24–28
نویسندگان
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