Noninvasive monitoring of colonic carcinogenesis: feasibility of [18F]FDG-PET in the azoxymethane model

Adenocarcinomas had a significantly higher [18F]FDG uptake than background bowel uptake. [18F]FDG uptake was lower in adenomas than in carcinomas. These data suggest that the AOM model allows the evaluation of intervention strategies with [18F]FDG uptake as a valid outcome measure.