کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2177988 1549623 2015 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Plummer Vinson syndrome in a male and his chromosomal study - A case report
ترجمه فارسی عنوان
سندرم پلومر وینسون در یک مطالعه کروموزومی مرد و زن - گزارش مورد
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
چکیده انگلیسی
Plummer Vinson syndrome (PVS) is a triad of iron deficiency anemia, esophageal web and dysphagia. The exact etiology of PVS remains controversial but it has been associated with nutritional deficiency, autoimmune disorders, hereditary factors and remarkable high female predominance. This paper reports an atypical presentation of PVS in a 38 year old Indian male with special emphasis given on chromosomal analysis. Chromosomal assessment is done as it is a good predictor of the possibility of development of post-cricoid carcinoma (PCC) in patients with PVS. Chromosomal aberrations like translocation, gain, loss, breakpoints and duplications are studied and they revealed normal male chromosomal pairing.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Egyptian Journal of Medical Human Genetics - Volume 16, Issue 3, July 2015, Pages 283-286
نویسندگان
, , ,