Nociceptin/orphanin FQ and stress regulate synaptophysin expression in the rat fundic and colonic mucosa

- Stress increases immunostained nerve fibers in the fundus.
- 4 h infusion of nociceptin/orphanin FQ increases immunostained fibers in the fundus.
- Immunostained cells are increased in the fundus of NOP (−/−) rats.
- Immunostained fibers are decreased in the fundus and colon of NOP (−/−) rats.