کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
228227 | 464836 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
BMP-2 immobilization by phosphonated UV-curable low-molecular-weight chitosan derivative on the surface of titanium
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
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چکیده انگلیسی
The purpose of this study is to immobilize growth factors and coat titanium surfaces using phosphonated UV-curable low-molecular-weight chitosan (Az-P-LM-O-CMC). The structure of the final product was assessed with FT-IR, 31P-NMR, and GPC. The coating of Az-P-LM-O-CMC on titanium was evaluated by measuring water contact angle. Cytotoxicity testing was conducted to determine biocompatibility, and micropatterning was used to check protein immobilization. From the BMP-2 release tests, it was observed that the rate of BMP-2 release could be controlled by multilayer coatings. ALP assay and Ca2+ assay were carried out to evaluate drug immobilization and release effects.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Industrial and Engineering Chemistry - Volume 34, 25 February 2016, Pages 33–40
Journal: Journal of Industrial and Engineering Chemistry - Volume 34, 25 February 2016, Pages 33–40
نویسندگان
Jin-Hong Jeong, Eun-Hye Kim, Ga-Dug Han, Jae-Woon Nah, Yoshihiro Ito, Tae-Il Son,