کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
228879 464852 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preparation of poly-lactic acid nano/microparticles using supercritical anti-solvent with enhanced mass transfer
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Preparation of poly-lactic acid nano/microparticles using supercritical anti-solvent with enhanced mass transfer
چکیده انگلیسی

Supercritical anti-solvent precipitation with enhanced mass transfer (SAS-EM) was applied for the production of micro and sub-microparticles of poly-lactic acid (PLA). SAS-EM technique uses an ultrasonic vibrating surface to enhance mass transfer rate between supercritical CO2 and solvent. Without applying ultrasonic power, which is same as SAS process, PLA particles with average diameters ranging between 1 μm and 3 μm were obtained. Using SAS-EM with the power supply of 200 W, spherical PLA particles smaller than 1 μm were obtained. The particle size was able to be controlled in the range of 0.4 μm–1.0 μm, by adjusting the power supply of ultrasonic field, the system pressure and temperature.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Industrial and Engineering Chemistry - Volume 16, Issue 1, 25 January 2010, Pages 101–105
نویسندگان
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