کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
228879 | 464852 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Preparation of poly-lactic acid nano/microparticles using supercritical anti-solvent with enhanced mass transfer
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
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چکیده انگلیسی
Supercritical anti-solvent precipitation with enhanced mass transfer (SAS-EM) was applied for the production of micro and sub-microparticles of poly-lactic acid (PLA). SAS-EM technique uses an ultrasonic vibrating surface to enhance mass transfer rate between supercritical CO2 and solvent. Without applying ultrasonic power, which is same as SAS process, PLA particles with average diameters ranging between 1 μm and 3 μm were obtained. Using SAS-EM with the power supply of 200 W, spherical PLA particles smaller than 1 μm were obtained. The particle size was able to be controlled in the range of 0.4 μm–1.0 μm, by adjusting the power supply of ultrasonic field, the system pressure and temperature.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Industrial and Engineering Chemistry - Volume 16, Issue 1, 25 January 2010, Pages 101–105
Journal: Journal of Industrial and Engineering Chemistry - Volume 16, Issue 1, 25 January 2010, Pages 101–105
نویسندگان
Sang Joon Park, Seoung Heon Choi, Hyon Hee Yoon,