Synthesis, spectroscopic characterization of some Schiff base complexes derived from 2-methylcyclohexanone and their activity against some fungi

New cobalt(II) and nickel(II) complexes of 4N-substituted thiosemicarbazones derivatives of 2-methylcyclohexanone of general composition ML2X2 (where M = Co(II) and Ni(II), X = Cl−, SCN− and ½ SO42-) have been prepared and characterized by elemental analysis, molar conductance, magnetic susceptibility measurements and spectral (IR, electronic, mass and EPR) techniques. Thiosemicarbazones exist in thione form and coordinate to metal ion through sulphur atom of CS group and azomethine nitrogen. Spectral studies suggest an octahedral geometry for all the complexes. The complexes and ligands have also been tested in vitro for their antifungal activity. The experimental results suggest that metal chelates are more potent than their parent ligands.