Effect of feed frame design and operating parameters on powder attrition, particle breakage, and powder properties

Feed frame is a device used in rotary tablet presses to drive the powders into compression dies. It applies shear forces to the powders as they are stirred around the feed frame chambers. This study focused on understanding the particle attrition, powder properties and the flow property changes of the material processed. The results demonstrated that the impact of the feed frame and die disk on the particle size distribution (PSD) outlet depended on the initial mean particle size, the die size and the powder outlet position. It also impacted the flow properties. The scale-up effect using a feed frame for a high production tablet press shows a significant increment in powder attrition.

This paper studies systematically the effect of feed frames on the properties of powder entering the dies. The work focused on the effect of blend particle size distribution, feed frame parameters, and rotary die disk parameters on powder attrition, the flow properties of the blends, and the scale-up effect using a feed frame for a high production tablet press.Figure optionsDownload as PowerPoint slideHighlights
► Tablet press feed frame effect on particle attrition.
► Powder properties changes as a function of feed frame and die disc speed.
► Study the scale-up effect using a feed frame for a high production tablet press.
► The feed frame scale-up significantly increases the powder attrition.