Properties of arsenic sulphide As4S4 nanoparticles prepared by high-energy milling

In this study, the nanosized arsenic sulphide As4S4 particles have been prepared by mechanical activation in a planetary mill. The bulk and surface properties of the milled particles were characterized by XRD and XPS methods as well as by surface area and particle size distribution measurements. For assessment of arsenic sulphide biological activity, the viability tests of multiple myeloma cancer cells have been applied. The obtained results show the arsenic sulphide nanoparticles properly milled and modified by mechanical activation can be valuated as a potential drug for cancer treatment.

We studied the effect of high-energy milling on the solid state properties and biological activity of arsenic sulphide As4S4. It was shown, that arsenic sulphide properly milled and modified by mechanical activation can be valuated as a potential drug for cancer treatment.Figure optionsDownload as PowerPoint slideResearch highlights
► The nanosized arsenic sulphide As4S4 particles have been prepared by mechanical activation in a planetary mill.
► The prepared nanoparticles show positive effect in reducing viability of multiple myeloma cancer cells.
► The obtained results show the nanoparticles can be valuated as a potential drug for cancer treatment.