Polymeric microparticles prepared by supercritical antisolvent precipitation

A method for precipitate Eudragit EPO® polymer in form of microparticles using supercritical carbon dioxide as antisolvent is reported. Microparticles were precipitated under 8 MPa and 313 K supercritical conditions. The mean size of the obtained microcapsules ranges between 2 and 12 μm.