کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2394134 1101379 2007 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
PPARγ and GLUT-4 expression as developmental regulators/markers for preadipocyte differentiation into an adipocyte
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
PPARγ and GLUT-4 expression as developmental regulators/markers for preadipocyte differentiation into an adipocyte
چکیده انگلیسی

In this document, we have integrated knowledge about two major cellular markers found in cells of the adipocyte lineage (an adipogenic marker and a metabolic marker). This review provides information as to how differentiation of a cell (such as an adipofibroblast, fibroblast or preadipocyte) to become a viable (and new) adipocyte is under different regulation than that experienced by an immature adipocyte that is just beginning to accumulate lipid. The differentiation, prior to lipid-filling, involves PPARγ. Subsequently, lipid-filling of the adipocyte relies on a late subset of genes and, depending on depot specificity, involves GLUT-4 or any number of other metabolic markers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Domestic Animal Endocrinology - Volume 33, Issue 4, November 2007, Pages 367–378
نویسندگان
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