کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
239439 | 465829 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Correlation between the micromorphological parameters and residual solvent content of a crystalline steroid drug
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
مهندسی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Correlation between the micromorphological parameters and residual solvent content of a crystalline steroid drug Correlation between the micromorphological parameters and residual solvent content of a crystalline steroid drug](/preview/png/239439.png)
چکیده انگلیسی
A small amount of solvents applied at the production of solid drugs is retained in the porous structure of the crystalline product. The regulatory guidelines require that the impurity due to the remaining solvent content of drugs should be a matter for serious concern toward marketing drugs; hence the reduction of the solvent amount is an important task of the technology of production. A steroid drug was crystallized and the correlation between the pore structure of the crystalline product and its residual solvent content was investigated. It was stated that the drug examined has a characteristic meso- and macropore structure, which distribution has a major contribution on the amount of the residual solvent content.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Powder Technology - Volume 167, Issue 2, 15 September 2006, Pages 104–107
Journal: Powder Technology - Volume 167, Issue 2, 15 September 2006, Pages 104–107
نویسندگان
Magdolna Hasznos-Nezdei, József Kovács, Sándor Kováts, Amir Bashiri Shahroodi, Piroska Szabó-Révész,