کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2395738 | 1101581 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Comparison of Diclofenac Diethylamine Permeation Across Horse Skin from Five Commercial Medical Human Formulations
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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![عکس صفحه اول مقاله: Comparison of Diclofenac Diethylamine Permeation Across Horse Skin from Five Commercial Medical Human Formulations Comparison of Diclofenac Diethylamine Permeation Across Horse Skin from Five Commercial Medical Human Formulations](/preview/png/2395738.png)
چکیده انگلیسی
The aim of this study was to compare the penetration of diclofenac through horse skin in vitro and its efficacy in vivo when applied from five, commercially available, human medical formulations containing 1.16% diclofenac diethylamine. The rate of transdermal penetration of diclofenac varied between formulations. Also, estimated steady-state flux (Jss) was significantly different from that reported for human and rat skin. All the tested formulations produced a very weak and short-lasting antiedematous effect.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Equine Veterinary Science - Volume 31, Issue 9, September 2011, Pages 502–505
Journal: Journal of Equine Veterinary Science - Volume 31, Issue 9, September 2011, Pages 502–505
نویسندگان
Alfredo Andreeta, Claudio Verde, Maximo Babusci, Raul Muller, Maria I. Simpson, Maria Fabiana Landoni,