کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2461550 1555034 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Advances in swine immunology help move vaccine technology forward
ترجمه فارسی عنوان
پیشرفت در ایمونولوژی خوک کمک به حرکت فن آوری واکسن به جلو است
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی

In veterinary animal species, vaccines are the primary tool for disease prevention, a key tool for treatment of infection, and essential for helping maintain animal welfare and productivity. Traditional vaccine development by trial-and-error has achieved many successes. However, effective vaccines that provide solid cross-protective immunity with excellent safety are still needed for many diseases. The path to development of vaccines against difficult pathogens requires recognition of uniquely evolved immunological interactions of individual animal hosts and their specific pathogens. Here, general principles that currently guide veterinary immunology and vaccinology research are reviewed, with an emphasis on examples from swine. Advances in genomics and proteomics now provide the community with powerful tools for elucidation of regulatory and effector mechanisms of protective immunity that provide new opportunities for successful translation of immunological discoveries into safe and effective vaccines.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Immunology and Immunopathology - Volume 159, Issues 3–4, 15 June 2014, Pages 202–207
نویسندگان
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