کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2463178 | 1555107 | 2007 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Idiotype expression of IgG1 and IgG2 in dogs naturally infected with Leishmania infantum
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
IgG1 and IgG2 responses in symptomatic and asymptomatic L. infantum infections differed mainly in subclass production (ELISA values), with higher IgG2 production occurring particularly in symptomatic dogs. Nevertheless, we observed little difference in the idiotype expression of these IgG subclasses, which, in general, recognized the same antigenic fractions. While early L. infantum infection was characterized by recognition of polypeptide fractions of low molecular weight, mainly fractions of 14, 16 and 18Â kDa by IgG1 and 14 and 16Â kDa by IgG2, symptomatology was associated with recognition by both IgG subclasses of a 24Â kDa fraction and other antigens belonging to the AG24 family.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Immunology and Immunopathology - Volume 119, Issues 3â4, 15 October 2007, Pages 189-197
Journal: Veterinary Immunology and Immunopathology - Volume 119, Issues 3â4, 15 October 2007, Pages 189-197
نویسندگان
Laura Iniesta, Montserrat Gállego, Montserrat Portús,