کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2464069 1111772 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cobalamin in companion animals: Diagnostic marker, deficiency states and therapeutic implications
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Cobalamin in companion animals: Diagnostic marker, deficiency states and therapeutic implications
چکیده انگلیسی

Measurement of the water-soluble vitamin cobalamin has long been of interest as a marker of gastrointestinal disease in companion animals due to the highly localized presence of cobalamin receptors in the ileum. An increasing body of evidence suggests that cobalamin deficiency is an important co-morbidity in many companion animal patients with gastrointestinal and pancreatic disease. Congenital disorders of cobalamin absorption and cellular metabolism are also increasingly recognized in companion animal breeds. The early recognition of these disorders and timely treatment with parenteral cobalamin can be life-saving. In this article, the normal mechanisms of cobalamin absorption, the use of cobalamin as a marker of intestinal disease and data on the prevalence of hypocobalaminemia in a variety of diseases are described. The prognostic impact of and rational therapy for hypocobalaminemia in domestic animals are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Veterinary Journal - Volume 196, Issue 2, May 2013, Pages 145–152
نویسندگان
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