کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2464656 1111804 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biology, diagnosis and treatment of canine appendicular osteosarcoma: Similarities and differences with human osteosarcoma
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Biology, diagnosis and treatment of canine appendicular osteosarcoma: Similarities and differences with human osteosarcoma
چکیده انگلیسی

Osteosarcoma (OSA) is the most common primary bone tumour in dogs. The appendicular locations are most frequently involved and large to giant breed dogs are commonly affected, with a median age of 7–8 years. OSA is a locally invasive neoplasm with a high rate of metastasis, mostly to the lungs. Due to similarities in biology and treatment of OSA in dogs and humans, canine OSA represents a valid and important tumour model. Differences between canine and human OSAs include the age of occurrence (OSA is most commonly an adolescent disease in humans), localisation (the stifle is the most common site of localisation in humans) and limited use of neoadjuvant chemotherapy in canine OSA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Veterinary Journal - Volume 189, Issue 3, September 2011, Pages 268–277
نویسندگان
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