کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2464982 1111814 2010 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel day blindness in sheep: Epidemiological, behavioural, electrophysiological and histopathological studies
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
A novel day blindness in sheep: Epidemiological, behavioural, electrophysiological and histopathological studies
چکیده انگلیسی

Four genetically related Improved Awassi sheep flocks had sporadic births of lambs with congenital visual impairments that differed from other known forms of sheep blindness. Pedigree analysis suggested an autosomal recessive mode of inheritance. Behavioural studies of 4-month old affected lambs showed that their day vision (but not night vision) was impaired. Electrophysiological results at this age demonstrated diminished function of cones but not rods. Histopathological and immunohistochemical evaluation of affected retinas from 5-month old lambs revealed both red-green and blue cones, suggesting that the behavioural day blindness and reduced cone electroretinograms reflect cone dysfunction rather than severe cone photoreceptor loss. Awassi day blindness may be a form of achromatopsia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Veterinary Journal - Volume 185, Issue 2, August 2010, Pages 130–137
نویسندگان
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