کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2465670 1111836 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Short-term effects of energy changes on plasma leptin concentrations and glucose tolerance in healthy ponies
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Short-term effects of energy changes on plasma leptin concentrations and glucose tolerance in healthy ponies
چکیده انگلیسی

To determine whether plasma leptin concentrations and glucose tolerance are affected by changes in energy balance, nine healthy Shetland ponies were fed at 140% followed by 75% of their maintenance requirements for 13 days in each of the two periods. Bodyweight was recorded every three days. Blood samples were taken every two days and analysed for leptin and cortisol. An oral glucose tolerance test was performed on day 7 of each period. Serial blood samples were analysed for glucose and insulin.Although bodyweight was not affected, plasma leptin concentrations increased (P < 0.001) initially during overfeeding, but returned to previous values after 7 days. During underfeeding, plasma leptin concentrations decreased (P < 0.001). Underfeeding was associated with a higher AUC for plasma glucose (P = 0.02) and plasma insulin (P = 0.05) resulting in a decreased glucose tolerance (AUC glucose/AUC insulin; P = 0.008), probably due to a plasma cortisol increase caused by the reduced feed intake. It is concluded that changes in energy balance, without altering bodyweight, can influence plasma leptin concentrations in ponies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Veterinary Journal - Volume 178, Issue 2, November 2008, Pages 233–237
نویسندگان
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