کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2495769 1116085 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acetogenins from Annona muricata
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی پزشکی مولکولی
پیش نمایش صفحه اول مقاله
Acetogenins from Annona muricata
چکیده انگلیسی
Silica gel chromatography of the dichloromethane extract of the seeds of Annona muricata afforded annoreticuin-9-one (1), while the flesh of the fruit yielded cis-annoreticuin (2) and sabadelin (3). The structures of 1-3 were elucidated by extensive 1 D and 2D NMR spectroscopy and confirmed by mass spectrometry. Acetogenins 1 and 2 were first isolated from A. reticulata and A. montana, respectively. Acetogenin 1 was reported to exhibit cytotoxic activities against the human pancreatic tumor cell line (PACA-2), human prostate adenocarcinoma (PC-3) and human lung carcinoma (A-549), while 2 was reported to exhibit cytotoxicity against human hepatoma carcinoma cell line (Hep G2).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Pharmacognosy Journal - Volume 4, Issue 32, November–December 2012, Pages 32-37
نویسندگان
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