کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2656809 1564045 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Early Weight-Loss Success Identifies Nonresponders after a Lifestyle Intervention in a Worksite Diabetes Prevention Trial
ترجمه فارسی عنوان
موفقیت اولیه در از دست دادن وزن، افراد غیر واجد شرایط را پس از مداخله شیوه زندگی در یک دادرسی پیشگیری از دیابت در محل کار شناسایی می کند
کلمات کلیدی
جلوگیری از دیابت، موفقیت از دست دادن وزن، حساسیت، اختصاصی، ارزش پیش بینی کننده
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی

BackgroundPeople with prediabetes are at increased risk for developing type 2 diabetes mellitus. Weight reduction through lifestyle modification can significantly reduce diabetes risk. Yet, weight loss varies among individuals and some people do not achieve clinically meaningful weight loss after treatment.ObjectiveOur aim was to evaluate the time point and threshold for achieving ≥5% weight loss after completion of a 16-week worksite, lifestyle intervention for diabetes prevention.DesignWeight change before and after the behavioral intervention among participants randomized to the experimental group was examined.Participants/settingIndividuals with prediabetes aged 18 to 65 years with a body mass index (calculated as kg/m2) of 25 to 50 at Ohio State University were eligible.InterventionThe 16-week, group-based intervention, adapted from the Diabetes Prevention Program, was delivered to 32 participants in the experimental group.Main outcome measuresPercent weight loss was assessed weekly during the intervention and at 4- and 7-month follow-up.Statistical analyses performedLinear regression modeled the relationship between percent weight loss during month 1 of the intervention and percent weight loss at 4 and 7 months. Logistic regression modeled failure to lose ≥5% weight loss at 4 and 7 months using weekly weight change during the first month of intervention.ResultsPercent weight loss at intervention week 5 was significantly associated with percent weight loss at 4 and 7 months (all P<0.001). Only 11.1% and 12.5% of participants who failed to achieve a 2.5% weight-loss threshold during month 1 achieved ≥5% weight loss at months 4 and 7, respectively.ConclusionsThe first month of lifestyle treatment is a critical period for helping participants achieve weight loss. Otherwise, individuals who fail to achieve at least 2.5% weight loss may benefit from more intensive rescue efforts or stepped-care interventions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Academy of Nutrition and Dietetics - Volume 115, Issue 9, September 2015, Pages 1464–1471
نویسندگان
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