The Safe and Effective Use of Pharmacological Agents Used for Sedation During Radiological Procedures

The use of pharmacological agents to decrease the pain and anxiety associated with the performance of invasive and noninvasive radiological procedures is well documented. The use of such agents is also increasing. This article is intended both as a review for the nonanesthesia professional administering these agents and a primer for those who wish to administer these agents. The physiological mechanisms by which anxiety occurs, and is modulated, are discussed, as are those surrounding pain. A discussion of the continuum of consciousness and sedation is discussed. Individual agents are reviewed, along with their strengths, weakness, warning, and contraindications. Finally, the safety and monitoring of the sedated patient is reviewed.