A cautionary note on the correct structure assignment of phytoprostanes and the emergence of a new prostane ring system

Considerable confusion exists about the correct structural representation of phytoprostanes (PhytoP). Improper use of the different nomenclature systems leads to incorrect structure assignment of PhytoP, which results in wrong synthetic approaches to these molecules and may lead to wrong rationalization of biological activity. A new prostane ring system was found, which is proposed to be termed L1-PhytoP or L2-IsoP, respectively.