کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2790175 1568581 2006 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Oxidant Status in Maternal and Cord Plasma and Placental Tissue in Gestational Diabetes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
Oxidant Status in Maternal and Cord Plasma and Placental Tissue in Gestational Diabetes
چکیده انگلیسی

The aim of this study was to measure oxidant/antioxidant status in maternal and cord plasma and in placental tissue in gestational diabetes and to correlate the results with the quality of glycemic control of the mother. To achieve this, blood and placental tissue samples have been obtained from pregnant women with gestational diabetes mellitus (GDM) and from the umbilical cord of their fetuses. The same samples have been collected from pregnant women without GDM. In all the samples, oxidant and antioxidant parameters have been studied. It has been observed that the antioxidant defense system was impaired; xanthine oxidase, which is the main free radical-producing enzyme (XO) in the living cells, was activated; and oxidation reactions were accelerated in the samples obtained from patients with GDM. Results suggest presence of oxidant stress in the gestational diabetes, the reason probably being impaired antioxidant defense mechanism and increased free radical production through XO activation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Placenta - Volume 27, Issues 2–3, February–March 2006, Pages 327–332
نویسندگان
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