The insulin-like growth factor (IGF)-system in active ulcerative colitis and Crohn's disease: Relations to disease activity and corticosteroid treatment

Significant changes in total and free IGF-I and IGFBP-2 and IGFBP-3 were demonstrated in CD and UC patients in exacerbation with only partial normalization during high dose corticosteroid treatment and tapering without differences between UC and CD. These changes may be part of MBD and MW in active IBD.