کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2808430 | 1157755 | 2008 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos](/preview/png/2808430.png)
چکیده انگلیسی
In order to further test whether or not psychostimulant drugs activate CART peptide-containing cells in the nucleus accumbens, we examined the fraction of CART positive cells that co-immunostained for c-Fos after administration of saline or cocaine (10 and 25 mg/kg i.p.). There was about a 45% increase in the fraction of cells that stained for both CART and c-Fos after administration of cocaine, but there was no change in the fraction after administration of saline. Moreover, the increase was not found 24 h after injection and is therefore reversible. These results support the notion that psychostimulant drugs activate CART cells in the nucleus accumbens, even under conditions where it is difficult to show a change in CART levels.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropeptides - Volume 42, Issue 3, June 2008, Pages 339–343
Journal: Neuropeptides - Volume 42, Issue 3, June 2008, Pages 339–343
نویسندگان
G.W. Hubert, M.J. Kuhar,