کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2815749 | 1159890 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis p130Cas/BCAR1 scaffold protein in tissue homeostasis and pathogenesis](/preview/png/2815749.png)
چکیده انگلیسی
BCAR1 (also known as p130Cas/BCAR1) is an adaptor protein that belongs to the CAS family of scaffold proteins. In the past years, increasing evidence has demonstrated the ability of p130Cas/BCAR1 to activate signaling originating from mechanical stimuli, cell–extracellular matrix (ECM) adhesion and growth factor stimulation cascades during normal development and disease in various biological models. In this review we will specifically discuss the more recent data on the contribution of p130Cas/BCAR1 in the regulation of tissue homeostasis and its potential implications in pathological conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 562, Issue 1, 10 May 2015, Pages 1–7
Journal: Gene - Volume 562, Issue 1, 10 May 2015, Pages 1–7
نویسندگان
Maria del Pilar Camacho Leal, Marianna Sciortino, Giusy Tornillo, Shana Colombo, Paola Defilippi, Sara Cabodi,