کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2818666 | 1569882 | 2010 | 15 صفحه PDF | دانلود رایگان |
Ardmore is a novel mycobacteriophage isolated from a soil sample collected in County Waterford, Ireland. The genome of this phage has been fully sequenced and is composed of 52,141 bp of linear double stranded DNA with a GC content of 61.49%. 88 ORFs were identified of which 34 were assigned predicted functions based on their homology to previously characterised proteins, their location in the genome, computer-predicted structural characteristics or presence of conserved motifs in their sequence. The Ardmore genome appears highly similar to mycobacteriophages Fruitloop and Tweety with BLASTn analysis showing 87% and 80% identity respectively. A predicted β-lactamase gene was detected in the sequence, and an unusual + 1 frameshift event for the translation of tail genes was also observed.
Journal: Gene - Volume 453, Issues 1–2, 15 March 2010, Pages 9–23