کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2819479 | 1569923 | 2008 | 11 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Bov-B-mobilized SINEs in vertebrate genomes Bov-B-mobilized SINEs in vertebrate genomes](/preview/png/2819479.png)
Two new short retroposon families (SINEs) have been found in the genome of springhare Pedetes capensis (Rodentia). One of them, Ped-1, originated from 5S rRNA, while the other one, Ped-2, originated from tRNA-derived SINE ID. In contrast to most currently active mammalian SINEs mobilized by L1 long retrotransposon (LINE), Ped-1 and Ped-2 are mobilized by Bov-B, a LINE family of the widely distributed RTE clade. The 3′ part of these SINEs originates from two sequences in the 5′ and 3′ regions of Bov-B. Such bipartite structure of the LINE-derived part has been revealed in all Bov-B-mobilized SINEs known to date (AfroSINE, Bov-tA, Mar-1, and Ped-1/2), which distinguishes them from other SINEs with only a 3′ LINE-derived part. Structural analysis and the distribution of Bov-B LINEs and partner SINEs supports the horizontal transfer of Bov-B, while the SINEs emerged independently in lineages with this LINE.
Journal: Gene - Volume 407, Issues 1–2, 15 January 2008, Pages 75–85